Document Detail


Dermoscopy of Lentigo Maligna Melanoma: Report of 125 Cases.
MedLine Citation:
PMID:  22404578     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background Lentigo maligna melanoma (LMM) is the most common subtype of melanoma on face. Presentation may be quite subtle particularly in early stages and delayed diagnosis is common. Few dermoscopic studies have been done and the main dermoscopic features of LMM have been defined by W. Stolz and co-workers in 2000. Objective We aimed to investigate classical as well as new dermoscopic features in a large series of LMM in a white-skinned population, in order to evaluate their diagnostic value. Patients and methods 125 consecutive histopathology-proven LMM were analysed retrospectively based on medical records, clinical and dermoscopic photographs by three independent observers for the presence of nine-teen predefined criteria. Results At least one of classical Stolz's criterion was present in 87% of cases (hyperpigmented follicular opening, annular-granular pattern, pigmented rhomboidal structures, obliterated hair follicles). Three original criteria were also present with a relatively high frequency: increase density of the vascular network (58%), red rhomboidal structures (40%), target-like patterns (41%). Darkening at dermoscopical examination (when compared to naked-eye examination) was observed in 25% of lesions. Classical extra-facial melanoma dermoscopic features (atypical pigment network, irregularly distributed globules, dots, streaks and pseudopods) and vertical growth phase-associated dermoscopic criteria (ulceration, blue papular areas and black structureless areas) were rarely seen. A large number of colours, pigmented rhomboidal structures, obliterated hair follicles and red rhomboidal structures were significantly more frequent in invasive lentigo maligna melanomas. On the opposite, in situ melanoma were more often associated with mono or bichromy and few of distinctive dermoscopic symptoms. Conclusion We present herein, in a large series of LMM, the confirmation of the diagnostic value of Stolz's classical dermoscopic criteria and of the interest of four additional original criteria, mainly vascular. A correlation between the presence of some dermoscopic features and thicker tumoral invasion has also been demonstrated.
Authors:
P Pralong; E Bathelier; S Dalle; N Poulalhon; S Debarbieux; L Thomas
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-8
Journal Detail:
Title:  The British journal of dermatology     Volume:  -     ISSN:  1365-2133     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
©The Authors BJD © 2012 British Association of Dermatologists.
Affiliation:
Department of Dermatology, Lyon 1 University, Centre Hospitalier Lyon Sud, 69495 Pierre Bénite Cedex, France.
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