Document Detail


Dermatomyositis in 132 patients with different clinical subtypes: cutaneous signs, constitutional symptoms and circulating antibodies.
MedLine Citation:
PMID:  12013199     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We retrospectively studied 132 patients with dermatomyositis; 84 had idiopathic, 30 paraneoplastic, 5 juvenile and 13 amyopathic forms of the disease. The commonest features were macular erythema, heliotropic erythema and Gottron's papules. Flagellate erythema occurred in 5% of patients with idiopathic dermatomyositis and correlated with the disease activity. Necrotic lesions were also found in this group of patients but did not always signal malignancy. The prevalence of malignancy was high (23%). Raynaud's phenomenon occurred in 10.6% of patients, also in those with malignancy. Dysphagia, interstitial lung disease and arthralgias affected 20%, 8% and 40% of patients, respectively. Anti-Jo-1 antibodies were found in 5% of patients with idiopathic dermatomyositis and low titre ANA in 1/3 of patients. ANA did not correlate with the disease activity. We confirmed the data from the literature, but no cutaneous sign, constitutional symptom or circulating antibody was found marking a particular subtype of the disease.
Authors:
A Parodi; M Caproni; A V Marzano; C De Simone; M La Placa; P Quaglino; C Veller Fornasa; C Zane; M Vaccaro; M Papini; P Fabbri; A Rebora
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  82     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  2002  
Date Detail:
Created Date:  2002-05-15     Completed Date:  2002-11-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  48-51     Citation Subset:  IM    
Affiliation:
Department of Endocrinological and Metabolic Diseases, University of Genoa, Genova, Italy. rebdermo@unige.it
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Biopsy, Needle
Chi-Square Distribution
Child
Child, Preschool
Dermatomyositis / epidemiology*,  pathology*
Female
Humans
Immunohistochemistry
Incidence
Italy / epidemiology
Male
Middle Aged
Probability
Retrospective Studies
Risk Factors
Sex Distribution

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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