Document Detail


Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
MedLine Citation:
PMID:  18604537     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.
Authors:
Uwe Lange; Peter Oelzner; Christine Uhlemann
Related Documents :
19623287 - Mastocytosis: a disease of the hematopoietic stem cell.
23432807 - An autoinflammatory neurological disease due to interleukin 6 hypersecretion.
20184077 - Extra-mammary paget's disease of the scrotum and penis: a case report.
10803707 - Weber-christian disease presenting with proptosis: a case report.
18552327 - Use of laboratory data to reduce the time taken to detect new diseases: vida to farmfile.
18992407 - Emerging infections: a perpetual challenge.
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-07-05
Journal Detail:
Title:  Rheumatology international     Volume:  29     ISSN:  0172-8172     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-09-30     Completed Date:  2009-04-24     Revised Date:  2013-08-21    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  17-22     Citation Subset:  IM    
Affiliation:
Kerckhoff-Clinic, Bad Nauheim, Germany, U.Lange@kerckhoff-klinik.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / pathology
Adiposis Dolorosa / complications,  pathology,  therapy*
Analgesics / therapeutic use*
Female
Humans
Hyperalgesia / drug therapy,  etiology,  pathology
Lymphedema / etiology,  pathology,  therapy*
Middle Aged
Suction / methods*
Treatment Outcome
gamma-Aminobutyric Acid / analogs & derivatives*,  therapeutic use
Chemical
Reg. No./Substance:
0/Analgesics; 55JG375S6M/pregabalin; 56-12-2/gamma-Aminobutyric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Precancerous lesions of the urothelium. From Feulgen staining to single cell CGH
Next Document:  Differentiation of total occlusion and high-grade stenosis in coronary CT angiography.