Document Detail

Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
MedLine Citation:
PMID:  18604537     Owner:  NLM     Status:  MEDLINE    
Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.
Uwe Lange; Peter Oelzner; Christine Uhlemann
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-07-05
Journal Detail:
Title:  Rheumatology international     Volume:  29     ISSN:  0172-8172     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-09-30     Completed Date:  2009-04-24     Revised Date:  2013-08-21    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  17-22     Citation Subset:  IM    
Kerckhoff-Clinic, Bad Nauheim, Germany,
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MeSH Terms
Adipose Tissue / pathology
Adiposis Dolorosa / complications,  pathology,  therapy*
Analgesics / therapeutic use*
Hyperalgesia / drug therapy,  etiology,  pathology
Lymphedema / etiology,  pathology,  therapy*
Middle Aged
Suction / methods*
Treatment Outcome
gamma-Aminobutyric Acid / analogs & derivatives*,  therapeutic use
Reg. No./Substance:
0/Analgesics; 55JG375S6M/pregabalin; 56-12-2/gamma-Aminobutyric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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