Document Detail

Deprivation, ethnicity and prematurity in infant respiratory failure in PICU in the UK.
MedLine Citation:
PMID:  20236254     Owner:  NLM     Status:  MEDLINE    
AIM: To describe the epidemiology of infants admitted to Paediatric Intensive Care (PIC) with acute respiratory failure including bronchiolitis. METHODS: Data from all consecutive admissions from 2004 to 2007 in all 29 designated Paediatric Intensive Care Units (PICUs) in England and Wales were collected. Admission rates, risk-adjusted mortality, length of stay, ventilation status, preterm birth, deprivation and ethnicity were studied. RESULTS: A total of 4641 infants under 1 year of age had an unplanned admission to PIC with acute respiratory failure (ARF), an admission rate of 1.80 per 1000 infants per year. There was a reduced rate of admission with bronchiolitis in South Asian children admitted to PICU, which is not explained by case-mix. Children born preterm had a higher rate of admission and longer stay, but a similar low mortality. Risk-adjusted mortality was higher in South Asian infants and the highest in those with ARF (OR 1.76, 95% CI 1.20-2.57) compared with the rest of the PICU population. CONCLUSION: Acute respiratory failure in infants causes most of the seasonal variation in unplanned admission to intensive care. Socioeconomic deprivation and prematurity are additional risk factors for admission. Fewer South Asian infants are admitted to PICU with a diagnosis of bronchiolitis, but risk-adjusted mortality is higher in South Asian infants overall.
D R O'Donnell; R C Parslow; E S Draper
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-18
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1186-91     Citation Subset:  IM    
Cambridge University Clinical School, Department of Paediatrics, Addenbrooke's Hospital, Cambridge, UK.
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MeSH Terms
Asian Continental Ancestry Group / ethnology,  statistics & numerical data
Bronchiolitis / ethnology*
England / epidemiology
Health Status Disparities*
Hospitalization / statistics & numerical data
Infant Mortality / ethnology
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / ethnology*
Intensive Care Units, Pediatric
Length of Stay / statistics & numerical data
Respiratory Distress Syndrome, Newborn / ethnology*
Risk Factors
Socioeconomic Factors
Wales / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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