| Depressive Mood and Subsequent Cancer Diagnosis in Patients Undergoing a Colonoscopy. | |
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MedLine Citation:
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PMID: 22458989 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: In patients with clinical signs that may indicate a colorectal cancer, physicians may interpret the presence of a comorbid depressive mood as either increasing or decreasing the likelihood of cancer diagnosis. This study examined the association between depressive mood in candidates for a colonoscopy and subsequent diagnosis of cancer. METHODS: Ninety-four outpatients [35 men, mean age ± standard deviation (SD) = 56.2 ± 9.8 years, 59 women, mean age ± SD = 54.2 ± 12.9 years] were given the 13-item Beck Depression Inventory to assess depressive mood before undergoing a colonoscopy. Additional psychological, demographic, and clinical data were collected prior to the colonoscopy. RESULTS: The colonoscopy found a cancer in 18 patients (19.1%). Cancer patients were older (P = 0.015) and more likely to present with anemia (P < 0.001) and unexplained weight loss (P = 0.046). Depressive mood was associated with a subsequent diagnosis of cancer in women (P = 0.007), but not in men (P = 0.985). This association remained significant after adjustment for potential confounders in women (i.e. anemia and unexplained weight loss) (P = 0.014). CONCLUSIONS: In women with clinical signs that warrant a colonoscopy, comorbid depressive mood may be associated with an increased likelihood of colorectal cancer and should not delay the receipt of a guideline-based diagnosis procedure. |
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Authors:
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Gaëlle Abgrall-Barbry; Cédric Lemogne; Dominique Lamarque; Bérengère Leuret; Sarah Bydlowski; Raymond Jian; Nicolas Dantchev; Silla M Consoli |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-27 |
Journal Detail:
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Title: Psychosomatics Volume: - ISSN: 1545-7206 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376506 Medline TA: Psychosomatics Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 The Academy of Psychosomatic Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Université Paris Descartes, Sorbonne Paris Cité, Faculté de médecine, Paris, France; Assistance Publique-Hôpitaux de Paris, Department of Psychiatry, Hôtel-Dieu Hospital, Paris, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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