Document Detail


Depression predicts self-reported disease activity in systemic lupus erythematosus.
MedLine Citation:
PMID:  20937622     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease that can significantly impact both physiological and psychological functioning. In order to examine the relationship between psychological functioning and disease activity in SLE, we administered instruments that collected sociodemographic information and measured indices of disease activity and psychosocial functioning from 125 adult Hispanic and White patients with SLE. Patients were recruited from four healthcare settings in the greater Southern California area. Both cross-sectional and longitudinal relationships between depression and disease activity were evaluated. Cross-sectional findings revealed that depression and ethnicity were independently correlated with self-reported disease activity. Longitudinally, depression alone predicted self-reported disease activity. These data suggest that depression may play a significant role in the health status of SLE patients and serve as an important target for clinical intervention.
Authors:
Fn Carr; Pm Nicassio; Ml Ishimori; I Moldovan; E Katsaros; K Torralba; S Shinada; D Cooray; Dj Wallace; S Finck; M Jolly; Al Wilson; Mh Weisman
Publication Detail:
Type:  Journal Article     Date:  2010-10-11
Journal Detail:
Title:  Lupus     Volume:  20     ISSN:  1477-0962     ISO Abbreviation:  Lupus     Publication Date:  2011  
Date Detail:
Created Date:  2011-01-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  England    
Other Details:
Languages:  eng     Pagination:  80-4     Citation Subset:  IM    
Affiliation:
1California School of Professional Psychology, Alliant International University, Los Angeles, California, USA.
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