| Depressed outpatients treated with cognitive therapy or pharmacotherapy. A one-year follow-up. | |
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MedLine Citation:
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PMID: 7006557 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using a controlled, clinical-trial format, 44 nonpsychotic, nonbipolar, depressed outpatients were treated with cognitive therapy or imipramine hydrochloride over a 12-week period. Although both interventions were associated with significant reductions in levels of depression, the cognitive-therapy patients showed greater symptomatic improvement and a higher treatment-completion rate. A one-year naturalistic follow-up of the 35 subjects who completed the protocol revealed that although many of the patients had a variable clinical course, both original treatment groups remained generally well. Self-rated depressive symptomatology was significantly lower for those who, one year earlier, had completed cognitive therapy than for those who had been in the clinical trial's pharmacotherapy cell. While there were several other interesting trends in favor of the cognitive-therapy patients, none of the between-group differences were significant. The pragmatic and clinical implications of the followup results are discussed. |
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Authors:
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M Kovacs; A J Rush; A T Beck; S D Hollon |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of general psychiatry Volume: 38 ISSN: 0003-990X ISO Abbreviation: Arch. Gen. Psychiatry Publication Date: 1981 Jan |
Date Detail:
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Created Date: 1981-03-17 Completed Date: 1981-03-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372435 Medline TA: Arch Gen Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 33-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ambulatory Care Clinical Trials as Topic Cognition Depressive Disorder / diagnosis, therapy* Female Follow-Up Studies Humans Imipramine / therapeutic use* Male Middle Aged Patient Dropouts Psychiatric Status Rating Scales Psychotherapy / methods* |
| Grant Support | |
ID/Acronym/Agency:
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MH-30847/MH/NIMH NIH HHS; MH-30915-01/MH/NIMH NIH HHS; MH-35420-03/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-49-7/Imipramine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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