| Depressed affect as a cause of associated somatic problems. | |
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MedLine Citation:
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PMID: 229503 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Depressed affect as a cause of associated somatic problems is explored by means of data on affect, appetite, energy, and sleep collected from a community sample and from subsamples contacted after each of several time lags. The analysis of the data indicates that depressed affect is a cause of the major somatic problems associated with it. It is suspected that depressed affect involves continuing high density neural firing which, over a period of months, causes a reduction of post-synaptic biogenic amine receptor cell sensitivity in the brainstem, with the diencephalon as the major site. This results in a functional impairment responsible for the somatic problems. |
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Authors:
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B Brenner |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Psychological medicine Volume: 9 ISSN: 0033-2917 ISO Abbreviation: Psychol Med Publication Date: 1979 Nov |
Date Detail:
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Created Date: 1980-02-28 Completed Date: 1980-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1254142 Medline TA: Psychol Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 737-46 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Affect Brain / physiopathology Cross-Sectional Studies Depression / complications*, physiopathology Eating Disorders / etiology Fatigue / etiology Humans Longitudinal Studies Receptors, Neurotransmitter / physiology Sleep Disorders / etiology |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Neurotransmitter |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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