| Depot-medroxyprogesterone acetate injection (Depo-Provera): a highly effective contraceptive option with proven long-term safety. | |
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MedLine Citation:
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PMID: 12954518 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Depot-medroxyprogesterone acetate (Depo-Provera(R)) is a highly effective, nondaily hormonal contraceptive option that has been available in the United States for a decade, and worldwide for 40 years. Benefits and risks of hormonal therapy are often under scrutiny; however, long-term clinical experience has established the safety of this long-acting contraceptive. This article reviews the contraceptive efficacy, potential noncontraceptive health benefits and long-term safety of with regard to risk of cardiovascular events, breast and gynecologic malignancy and osteopenia. Comparisons with other hormonal contraceptives are made as clinically appropriate. Common patient management issues, including effects on menstrual cycle, body weight and mood, are also addressed. Finally, this review provides recommendations for appropriate patient selection. |
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Authors:
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Carolyn Westhoff |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Contraception Volume: 68 ISSN: 0010-7824 ISO Abbreviation: Contraception Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-09-04 Completed Date: 2004-03-15 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0234361 Medline TA: Contraception Country: United States |
Other Details:
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Languages: eng Pagination: 75-87 Citation Subset: IM |
Affiliation:
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School of Public Health, Columbia University, New York, NY 10032, USA. clw3@columbia.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contraceptive Agents, Female*
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adverse effects,
pharmacology Female Humans Medroxyprogesterone Acetate* / adverse effects, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Contraceptive Agents, Female; 71-58-9/Medroxyprogesterone Acetate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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