Document Detail

Depot medroxyprogesterone acetate: implications for weight status and bone mineral density in the adolescent female.
MedLine Citation:
PMID:  16183540     Owner:  NLM     Status:  MEDLINE    
Depot medroxyprogesterone acetate (DMPA) is an effective and easy-to-use contraceptive method for adolescents. However, recent literature suggests that overweight teens may be at increased risk for weight gain while on this contraceptive method, and decreases in bone mineral density have been documented in adolescents on DMPA, particularly with longer duration of use. Consideration of this new literature on DMPA and its implications for clinical practice must be done in the context of the United States having the highest adolescent pregnancy rate in the industrialized world. Hence, potential DMPA risks need to be weighed against the risk of unintended pregnancy in an adolescent.
Andrea E Bonny; Laura S Harkness; Barbara A Cromer
Publication Detail:
Type:  Journal Article; Meta-Analysis    
Journal Detail:
Title:  Adolescent medicine clinics     Volume:  16     ISSN:  1547-3368     ISO Abbreviation:  Adolesc Med Clin     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-26     Completed Date:  2006-02-15     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  101196463     Medline TA:  Adolesc Med Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  569-84     Citation Subset:  IM    
Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
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MeSH Terms
Body Composition / drug effects
Bone Density / drug effects*
Clinical Trials as Topic
Contraceptive Agents, Female / administration & dosage,  adverse effects*
Cross-Cultural Comparison
Medroxyprogesterone Acetate / administration & dosage,  adverse effects*
Obesity / physiopathology
Patient Dropouts
Pregnancy in Adolescence / prevention & control*,  psychology
Risk Factors
Weight Gain / drug effects*,  ethnology
Reg. No./Substance:
0/Contraceptive Agents, Female; 71-58-9/Medroxyprogesterone Acetate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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