Document Detail

Depiction of renal perfusion defects with contrast-enhanced harmonic sonography in a porcine model.
MedLine Citation:
PMID:  10470918     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Our purpose was to test the feasibility and optimization of contrast-enhanced gray-scale harmonic sonography for the evaluation of focal renal perfusion defects in an animal model. SUBJECTS AND METHODS: We performed arteriography and contrast-enhanced harmonic sonography on six anesthetized piglets after embolization of each kidney with an autologous clot through the main renal artery. Harmonic images were obtained with continuous (30 Hz) and ECG-triggered acquisition. The two harmonic sonography strategies were compared with respect to the number and conspicuity of devascularized areas, and correlation was made with arteriographic findings. RESULTS: Contrast-enhanced harmonic sonography showed focal areas of absent or diminished vascularity that corresponded closely with perfusion defects seen on angiography. Enhancement ratios to perfused cortex were significantly higher than to devascularized cortex in both continuous (mean +/- SD, 469 +/- 5% versus 102 +/- 8%, p < .0005 by t test) and triggered (673 +/- 7% versus 198 +/- 7%, p < .0001) modes. Triggered acquisition increased the conspicuity of perfusion defects over that obtained with continuous imaging (p < .002 by t test). CONCLUSION: Contrast-enhanced harmonic sonography is an effective method of depicting focal renal perfusion defects. Triggered acquisition further improves lesion conspicuity.
G A Taylor; C E Barnewolt; M Claudon; P S Dunning
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  173     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-09-21     Completed Date:  1999-09-21     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  757-60     Citation Subset:  AIM; IM    
Department of Radiology, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
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MeSH Terms
Contrast Media
Feasibility Studies
Image Processing, Computer-Assisted
Infarction / ultrasonography
Kidney / blood supply*,  ultrasonography*
Renal Artery Obstruction / ultrasonography
Renal Circulation
Thrombosis / ultrasonography
Ultrasonography / methods
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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