Document Detail

Dependence of the output of a halothane vaporizer on thymol concentration.
MedLine Citation:
PMID:  3232783     Owner:  NLM     Status:  MEDLINE    
The effect of thymol accumulation inside a Fluotec 3 vaporizer on the concentration of halothane delivered by the vaporizer was investigated. The vaporizer output was reduced progressively as the thymol concentration increased, but the reduction was less than that predicted by Raoult's Law. A reduction of 5% in output required an increase in thymol concentration of a factor of 650 compared to the concentration in fresh halothane, while a reduction of 10% required a 1100-fold increase in thymol concentration. The equilibration of the thymol from the wicks throughout the vaporizing chamber was very slow after the vaporizer was drained and filled with fresh halothane; the half-time was 2.7 days.
W M Gray
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  43     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1988 Dec 
Date Detail:
Created Date:  1989-04-14     Completed Date:  1989-04-14     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1047-9     Citation Subset:  AIM; IM    
Department of Clinical Physics and Bio-Engineering, Glasgow.
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MeSH Terms
Anesthesia, Inhalation / instrumentation
Halothane / administration & dosage*
Nebulizers and Vaporizers*
Thymol* / analysis
Time Factors
Reg. No./Substance:
151-67-7/Halothane; 89-83-8/Thymol

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