Document Detail


Dependence of Doppler echocardiographic transmitral early peak velocity on left ventricular systolic function in coronary artery disease.
MedLine Citation:
PMID:  1998278     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of systolic function on pulsed Doppler echocardiographic transmitral flow velocity patterns was assessed before and after postextrasystolic (PES) potentiation in 12 normal subjects (control group) and in 25 patients with previous healed myocardial infarction (MI) group. Simultaneous high-fidelity left ventricular pressure measurements were performed in all patients. A programmed single-coupled right ventricular extrasystole was induced during echocardiographic and subsequent cineangiocardiographic recordings. Adequate angiograms for volumetric analysis in both baseline and PES beats were obtained in 23 patients (7 in the control group and 16 in the MI group). PES potentiation of contraction was more pronounced in the MI group than in the control group. PES changes in ejection fraction, stroke volume and end-systolic volume were significantly greater in the MI group than in the control group (11 vs 5%, p less than 0.005; 15 vs 5 ml/m2, p less than 0.005; and -13 vs -4 ml/m2, p less than 0.01, respectively). In contrast, PES potentiation prolonged the time constants of left ventricular pressure decline derived from exponential curve fits with a zero (Tw) and non-zero (Tb) asymptote pressure in the MI group to the same extent as in the control group (4 vs 5 ms, difference not significant [NS], and 9 vs 11 ms, NS, respectively). In the PES beat, peak E velocity remained unaltered (48 vs 49 cm/s, NS) in the control group, whereas it increased significantly (p less than 0.0001) from 47 to 51 cm/s in the MI group.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
S Miki; T Murakami; T Iwase; T Tomita; Y Suzuki; C Kawai
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  67     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-04-01     Completed Date:  1991-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  470-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Kyoto University Hospital, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angiocardiography
Blood Flow Velocity
Coronary Disease / diagnosis,  physiopathology*,  radiography
Echocardiography, Doppler*
Female
Humans
Male
Middle Aged
Myocardial Contraction
Stroke Volume
Systole
Ventricular Function, Left*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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