| Dentinogenesis imperfecta: evidence of qualitative alteration in the organic dentin matrix. | |
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MedLine Citation:
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PMID: 6777477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Deciduous teeth affected by dentinogenesis imperfecta were obtained from two patients with osteogenesis imperfecta. Electronmicroscopy of the dentin revealed some structural alterations. The striation of the collagen fibrils was not clear, and the crystals were less dense than in normal dentin. The amino acid analysis of dentin collagen was slightly different from normal dentin. There were slight increases in the amounts of hydroxylysine, serine and acidic acids. On the other hand, lysine and arginine were reduced. The elevation of hexosyllysine content and an increase of carbohydrate were also observed. These results indicate that either dentin collagen is altered, or noncollagenous matrices associated with collagen are increased in dentinogenesis imperfecta dentin. |
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Authors:
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Y Takagi; H Koshiba; O Kimura; Y Kuboki; S Sasaki |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of oral pathology Volume: 9 ISSN: 0300-9777 ISO Abbreviation: J. Oral Pathol. Publication Date: 1980 Jul |
Date Detail:
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Created Date: 1981-02-19 Completed Date: 1981-02-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0342050 Medline TA: J Oral Pathol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 201-9 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Amino Acids / analysis Carbohydrates / analysis Child, Preschool Collagen / analysis Dentin / analysis, ultrastructure* Dentinogenesis Imperfecta / pathology* Female Humans Microscopy, Electron Tooth, Deciduous / analysis, ultrastructure |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Carbohydrates; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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