Document Detail

Dentinal tubule disinfection with 2% chlorhexidine gel, propolis, morinda citrifolia juice, 2% povidone iodine, and calcium hydroxide.
MedLine Citation:
PMID:  20518935     Owner:  NLM     Status:  MEDLINE    
AIM: To investigate the antimicrobial activity of 2% chlorhexidine gel, propolis, Morinda citrifolia juice (MCJ), 2% povidone Iodine (POV-I), and calcium hydroxide on Enterococcus faecalis-infected root canal dentine at two different depths (200 microm and 400 microm) and three time intervals (day 1, 3 & 5). METHODOLOGY: One hundred and eighty extracted human teeth were infected for 21 days with E. faecalis. Samples were divided into six groups. Group I (Saline) (Negative control), Group II (Propolis), Group III (MCJ), Group IV (2% Povidone Iodine), Group V (2% Chlorhexidine Gel), Group VI (Calcium hydroxide). At the end of 1, 3, and 5 days, the remaining vital bacterial population was assessed. Dentine shavings were collected at two depths (200 microm and 400 microm), and total numbers of colony forming units were determined. The values were analysed statistically with one-way analysis of variance followed by Tukey multiple comparison test. The paired t-test was used to check for differences in growth at different time intervals within groups and for differences at the two depths (P < 0.01) RESULTS: The number of colony-forming units was statistically significant in all groups compared to the control group (Saline). Group V (chlorhexidine gluconate) (100%) produced better antimicrobial efficacy followed by 2% POV-I (87%), propolis (71%), MCJ (69%), and calcium hydroxide (55%). There was no significant difference between propolis and MCJ and no significant difference between data at 200 microm and 400 microm. CONCLUSION: Propolis and MCJ were effective against E. faecalis in dentine of extracted teeth.
D Kandaswamy; N Venkateshbabu; D Gogulnath; A J Kindo
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International endodontic journal     Volume:  43     ISSN:  1365-2591     ISO Abbreviation:  Int Endod J     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-03     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8004996     Medline TA:  Int Endod J     Country:  England    
Other Details:
Languages:  eng     Pagination:  419-23     Citation Subset:  D    
Department of Conservative Dentistry and Endodontics, Sri Ramachandra Dental College, Porur, Chennai, India.
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MeSH Terms
Anti-Infective Agents, Local / therapeutic use*
Calcium Hydroxide / therapeutic use
Chlorhexidine / therapeutic use
Colony Count, Microbial
Dental Pulp Cavity / microbiology,  ultrastructure
Dentin / microbiology*,  ultrastructure
Enterococcus faecalis / drug effects
Materials Testing
Plant Extracts / therapeutic use
Povidone-Iodine / therapeutic use
Propolis / therapeutic use
Root Canal Irrigants / therapeutic use*
Time Factors
Reg. No./Substance:
0/Anti-Infective Agents, Local; 0/Plant Extracts; 0/Root Canal Irrigants; 1305-62-0/Calcium Hydroxide; 25655-41-8/Povidone-Iodine; 55-56-1/Chlorhexidine; 9009-62-5/Propolis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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