Document Detail

Dental and occlusal changes during mandibular advancement splint therapy in sleep disordered patients.
MedLine Citation:
PMID:  12938843     Owner:  NLM     Status:  MEDLINE    
The aims of this longitudinal, observational study were two-fold: first, to determine in adults with sleep disorders the extent of dental and occlusal changes following the use of a mandibular advancement splint (MAS) and, second, to determine the time course of these changes. One hundred adult subjects (87 males, 13 females) diagnosed with obstructive sleep apnoea (OSA) and/or asymptomatic snoring were treated with non-adjustable MAS. At the outset each subject was randomly assigned to a group and reviewed 6, 12, 18, 24 or 30 months after placement of a splint. There were 20 subjects in each group. Craniofacial changes were measured on lateral cephalometric radiographs taken at the initial and review appointments. When the changes in all subjects were examined, the SNA, ANB angles, ANS-PNS length and face height increased, and the mandibular first molars and the maxillary first premolars significantly overerupted. Significant retroclination of the maxillary incisors and proclination of the mandibular incisors were accompanied by reductions in maxillary arch length, overbite and overjet. When the changes over time were determined, the mandibular symphysis was significantly lower at all review periods. An increase in face height and reductions in overbite and overjet were evident at 6 months, and over-eruption of the maxillary first premolars and mandibular first molars, and proclination of the lower incisors were found at 24 months. Significant positive correlations were also found between the amount of anterior opening by the appliances and changes in overbite at 24 and 30 months. The appliance used produced small, unpredictable changes in the occlusion that tended to occur after 24 months' wear. It is postulated that the changes in overbite might be lessened by keeping the bite opening to a minimum.
Christopher Robertson; Peter Herbison; Michael Harkness
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of orthodontics     Volume:  25     ISSN:  0141-5387     ISO Abbreviation:  Eur J Orthod     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-08-26     Completed Date:  2003-11-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909010     Medline TA:  Eur J Orthod     Country:  England    
Other Details:
Languages:  eng     Pagination:  371-6     Citation Subset:  D; IM    
Department of Oral Sciences and Orthodontics, School of Dentistry, University of Otago, Dunedin, New Zealand.
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MeSH Terms
Bicuspid / pathology
Dental Arch / pathology
Follow-Up Studies
Incisor / pathology
Longitudinal Studies
Mandible / pathology
Mandibular Advancement / instrumentation*
Maxilla / pathology
Middle Aged
Molar / pathology
Nasal Bone / pathology
Sella Turcica / pathology
Sleep Apnea, Obstructive / therapy*
Snoring / therapy*
Vertical Dimension

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