Document Detail


Dengue hemorrhagic fever and shock syndromes.
MedLine Citation:
PMID:  20639791     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To provide a comprehensive review of dengue, with an emphasis on clinical syndromes, classification, diagnosis, and management, and to outline relevant aspects of epidemiology, immunopathogenesis, and prevention strategies. Dengue, a leading cause of childhood mortality in Asia and South America, is the most rapidly spreading and important arboviral disease in the world and has a geographic distribution of > 100 countries.
DATA SOURCE: Boolean searches were carried out by using PubMed from 1975 to March 2009 and the Cochrane Database of Systematic Reviews from 1993 to March 2009 to identify potentially relevant articles by key search terms such as: "dengue"; "dengue fever"; "dengue hemorrhagic fever"; "dengue shock syndrome"; "severe dengue" and "immunopathogenesis," pathogenesis," "classification," "complications," and "management." In addition, authoritative seminal and up-to-date reviews by experts were used.
STUDY SELECTION: Original research and up-to-date reviews and authoritative reviews consensus statements relevant to diagnosis and therapy were selected.
DATA EXTRACTION AND SYNTHESIS: We considered the most relevant articles that would be important and of interest to the critical care practitioner as well as authoritative consensus statements from the World Health Organization and the Centers for Disease Control and Prevention. Dengue viral infections are caused by one of four single-stranded ribonucleic acid viruses of the family Flaviviridae and are transmitted by their mosquito vector, Aedes aegypti. The clinical syndromes caused by dengue viral infections occur along a continuum; most cases are asymptomatic and few present with severe forms characterized by shock. Management is predominantly supportive and includes methods to judiciously resolve shock and control bleeding while at the same time preventing fluid overload.
CONCLUSIONS: Dengue is no longer confined to the tropics and is a global disease. Treatment is supportive. Outcomes can be optimized by early recognition and cautious titrated fluid replacement, especially in resource-limited environments.
Authors:
Suchitra Ranjit; Niranjan Kissoon
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  12     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-06     Completed Date:  2011-06-02     Revised Date:  2012-02-09    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  90-100     Citation Subset:  IM    
Affiliation:
Pediatric Intensive Care Unit, Apollo Children's Hospital, Chennai, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aedes / virology
Animals
Critical Care*
Dengue Hemorrhagic Fever* / complications,  diagnosis,  epidemiology,  therapy
Humans
Insect Vectors
Mosquito Control
Shock* / diagnosis,  epidemiology,  therapy,  virology
Syndrome
Comments/Corrections
Comment In:
Pediatr Crit Care Med. 2011 Nov;12(6):694   [PMID:  22067826 ]
Pediatr Crit Care Med. 2012 Jan;13(1):125; author reply 125-6   [PMID:  22222665 ]
Pediatr Crit Care Med. 2011 Jan;12(1):116-7   [PMID:  21209578 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Congenital blepharoptosis co-occurring with VATER association.
Next Document:  A randomized, double-blind, controlled trial of the effect of prebiotic oligosaccharides on enteral ...