| Denervation-induced changes in lectin binding to sarcolemmal glycoproteins: exposure of cryptic recognition sites. | |
| | |
MedLine Citation:
|
PMID: 1498418 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The increase in Concanavalin A (ConA) binding to sarcolemmal membranes of rat skeletal muscle following denervation has been attributed to conformational changes in membrane glycoproteins resulting in the unmasking of previously cryptic ConA binding sites (Leung et al., 1982). In this study, analysis of lectin binding patterns to alpha-fucosidase- or sialidase-treated sarcolemmal membranes reveals that the fucose moieties of carbohydrate structures may be principally involved in the unmasking process. By contrast, sialic acid has no apparent effect on the availability of the number of ConA binding sites, but plays a significant role in the masking of other lectin recognition sites. |
| | |
Authors:
|
R C Iannello; P L Jeffrey |
Related Documents
:
|
6617878 - Magnesium as a natural substitute for manganese in concanavalin a and other lectins. 1607368 - Alteration of the carbohydrate-binding specificity of the bauhinia purpurea lectin thro... 16501058 - It depends on the hinge: a structure-functional analysis of galectin-8, a tandem-repeat... 8405468 - The effect of sugars on the morphology of the bacterial flagellum. 10431358 - Study by means of high-performance liquid chromatography of solutes that decrease theop... 9038998 - Presence and activity of compounds with gnrh-like activity in the ovary of seabream spa... |
Publication Detail:
|
Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Glycobiology Volume: 2 ISSN: 0959-6658 ISO Abbreviation: Glycobiology Publication Date: 1992 Jun |
Date Detail:
|
Created Date: 1992-09-15 Completed Date: 1992-09-15 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9104124 Medline TA: Glycobiology Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 211-6 Citation Subset: IM |
Affiliation:
|
Murdoch Institute, Royal Children's Hospital, Melbourne, Victoria, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Binding Sites Female Kinetics Lectins / metabolism* Membrane Glycoproteins / chemistry, metabolism* Muscle Denervation Muscles / innervation, metabolism Neuraminidase Oligosaccharides / chemistry, metabolism Rats Rats, Inbred Strains Sarcolemma / metabolism* alpha-L-Fucosidase |
| Chemical | |
Reg. No./Substance:
|
0/Lectins; 0/Membrane Glycoproteins; 0/Oligosaccharides; EC 3.2.1.18/Neuraminidase; EC 3.2.1.51/alpha-L-Fucosidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A cardiac transplant programme--the nurses role.
Next Document: Development and characterization of monoclonal antibodies against a mucin-type glycoprotein.