| Dendritic nucleotides: interaction with an aliphatic acid monolayer. | |
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MedLine Citation:
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PMID: 18816520 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dendrimeric-T and dendrimeric-A with 36 nucleotides were synthesized using phosphoramidite reagents. These dendrimers contain the nucleosides dA and dT, which are the components of the dA-dT base pair. Branching was obtained using a bifurcated and trifurcated reagent. The dendrimers were purified by ion-exchange chromatography. No specific interactions between these dendrimers were observed using atomic force microscopy. However, the dendrimeric-T is able to disrupt monolayers of fatty acids, resulting in a reorientation of the lipids (from head-to-tail to head-to-head) as demonstrated by scanning tunneling microscopy (STM). |
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Authors:
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Guojie Wang; Mikhail Abramov; Arthur Van Aerschot; Jef Rozenski; Shengbin Lei; Andrei Klymchenko; Mark Van der Auweraer; Steven De Feyter; Piet Herdewijn |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Chemistry & biodiversity Volume: 5 ISSN: 1612-1880 ISO Abbreviation: Chem. Biodivers. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-10-01 Completed Date: 2008-11-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101197449 Medline TA: Chem Biodivers Country: Switzerland |
Other Details:
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Languages: eng Pagination: 1675-82 Citation Subset: IM |
Affiliation:
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Division of Molecular and Nanomaterials, Department of Chemistry, K.U. Leuven, Celestijnenlaan 200 F, BE-3001 Heverlee. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromatography, High Pressure Liquid Dendrimers / chemistry* Fatty Acids / chemistry* Microscopy, Atomic Force Microscopy, Scanning Tunneling Molecular Structure Nucleotides / chemical synthesis, chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Dendrimers; 0/Fatty Acids; 0/Nucleotides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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