| Dendritic cell function at the maternal-fetal interface. | |
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MedLine Citation:
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PMID: 21895472 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Understanding the evolutionary adaptation of the immune system to the developing fetus and placenta represents one of the most fascinating problems in reproductive biology. Recent work has focused on how the behavior of dendritic cells (DCs) is altered at the maternal-fetal interface to suit the unique requirements of pregnancy. This work has provided a significant new perspective into the long-standing immunological paradox of fetomaternal tolerance, and has opened up a new and intriguing area of research into the potential trophic role of uterine DCs in the peri-implantation period. Further research on the biology of uterine DCs promises to give insight into the pathogenesis of many clinically important disorders of pregnancy. |
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Authors:
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Elisa Tagliani; Adrian Erlebacher |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of clinical immunology Volume: 7 ISSN: 1744-8409 ISO Abbreviation: Expert Rev Clin Immunol Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101271248 Medline TA: Expert Rev Clin Immunol Country: England |
Other Details:
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Languages: eng Pagination: 593-602 Citation Subset: IM |
Affiliation:
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Department of Pathology, New York University School of Medicine, New York, NY 10016, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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