Document Detail


Demyelinating peripheral neuropathy in Devic disease.
MedLine Citation:
PMID:  1667535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a report of a 20-year-old man with typical features of Devic disease (neuromyelitis optica) associated with demyelinating peripheral neuropathy. A sural nerve biopsy showed markedly decreased myelinated fibers of a large diameter. Teased fiber preparations showed segmental remyelination in 50% of examined fibers, as well as a few demyelination. Demyelination of bilateral optic nerves, spinal cord, and peripheral nerves at the same time suggests a possibility of common pathogenetic mechanisms in both the central and peripheral nervous systems.
Authors:
Y Aimoto; K Ito; F Moriwaka; K Tashiro; K Abe
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Japanese journal of psychiatry and neurology     Volume:  45     ISSN:  0912-2036     ISO Abbreviation:  Jpn. J. Psychiatry Neurol.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-06-18     Completed Date:  1992-06-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8610886     Medline TA:  Jpn J Psychiatry Neurol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  861-4     Citation Subset:  IM    
Affiliation:
Department of Neurology, Hokkaido University School of Medicine, Sapporo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Central Nervous System Diseases / diagnosis
Demyelinating Diseases / etiology,  pathology*
Humans
Magnetic Resonance Imaging
Male
Neuromyelitis Optica / complications,  pathology*
Peripheral Nervous System Diseases / pathology
Sural Nerve / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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