| Demyelinating optic neuritis presenting as a clinically isolated syndrome. | |
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MedLine Citation:
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PMID: 22153821 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Clinically isolated syndrome (CIS) describes a single, first-occurrence attack caused by inflammation/demyelination in 1 or more locations in the central nervous system. The optic nerve is a frequent site affected by this neurologic event. As the name implies, CIS is an isolated condition but is often considered a precursor to multiple sclerosis (MS). When distinctive brain lesions detected by magnetic resonance imaging (MRI) accompany CIS, the person is considered at a high risk for MS. Treatment is aimed at delaying the onset of a second neurologic episode, reducing the accumulation of MRI-detected brain lesions and delaying the development of definite MS. CASE REPORT: This article describes a 40-year-old woman who experienced a sudden loss of vision in the right eye. Testing ultimately found a normal MRI, demyelination of the optic nerve, and progressive thinning of the retinal nerve fiber layer, leading to a diagnosis of CIS. |
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Authors:
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Nicky R Holdeman; Tammy Nguyen; Rosa A Tang |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Optometry (St. Louis, Mo.) Volume: 83 ISSN: 1558-1527 ISO Abbreviation: Optometry Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2011-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100912421 Medline TA: Optometry Country: United States |
Other Details:
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Languages: eng Pagination: 9-18 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 American Optometric Association. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Multiple Sclerosis Eye Center for Analysis, Research, & Education (MS-Eye CARE), University Eye Institute, University of Houston, Texas. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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