Document Detail

Demospongic acids revisited.
MedLine Citation:
PMID:  21116406     Owner:  NLM     Status:  MEDLINE    
The well-known fatty acids with a Δ5,9 unsaturation system were designated for a long period as demospongic acids, taking into account that they originally occurred in marine Demospongia sponges. However, such acids have also been observed in various marine sources with a large range of chain-lengths (C(16)-C(32)) and from some terrestrial plants with short acyl chains (C(18)-C(19)). Finally, the Δ5,9 fatty acids appear to be a particular type of non-methylene-interrupted fatty acids (NMA FAs). This article reviews the occurrence of these particular fatty acids in marine and terrestrial organisms and shows the biosynthetic connections between Δ5,9 fatty acids and other NMI FAs.
Jean-Michel Kornprobst; Gilles Barnathan
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-10-08
Journal Detail:
Title:  Marine drugs     Volume:  8     ISSN:  1660-3397     ISO Abbreviation:  Mar Drugs     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-30     Completed Date:  2011-06-22     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  101213729     Medline TA:  Mar Drugs     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  2569-77     Citation Subset:  IM    
Groupe Mer, Molécules, Santé MMS/EA 2160, Equipe 7: Lipides marins à activité biologique, Pôle Mer et Littoral, Faculté de Pharmacie, Université de Nantes, France.
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MeSH Terms
Fatty Acids* / biosynthesis,  chemistry,  classification,  metabolism
Oceans and Seas
Porifera / chemistry*,  classification,  metabolism*
Reg. No./Substance:
0/Fatty Acids

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