Document Detail


Demonstration of feline infectious peritonitis virus in conjunctival epithelial cells from cats. A simple and reliable method for clinical veterinary virology screening.
MedLine Citation:
PMID:  2551353     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A simple technique demonstrating the presence of feline infectious peritonitis virus (FIPV) in cats is described. Smears from the third eyelid (membrana nictitans) were dried on microscope slides, fixed in aetone, and stained using an indirect immunofluorescence method with rabbit-anti-FIPV serum. By this method FIPV-antigen could be demonstrated in the cytoplasma of epithelial cells. The results obtained with this method (M3) were compared with serological and immunohistopathological methods for confirming FIPV-infection in cats. The results obtained by the M3 test were up to 85% in concordance with these other tests. Furthermore, the M3 test was easier and quicker to perform and should be well suited for clinical practice.
Authors:
K Hök
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica     Volume:  97     ISSN:  0903-4641     ISO Abbreviation:  APMIS     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-11-08     Completed Date:  1989-11-08     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8803400     Medline TA:  APMIS     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  820-4     Citation Subset:  IM    
Affiliation:
Department of Medical Microbial Ecology, Karolinska Institutet, Stockholm, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigens, Viral / analysis
Cat Diseases / diagnosis*
Cats
Coronaviridae / immunology
Coronaviridae Infections / diagnosis,  veterinary*
Epithelium / microbiology
Fluorescent Antibody Technique
Nictitating Membrane / microbiology*
Peritonitis / diagnosis,  veterinary*
Chemical
Reg. No./Substance:
0/Antigens, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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