Document Detail


Demographics, treatment and outcome of acute coronary syndromes: 17 years of experience in a specialized cardiac centre.
MedLine Citation:
PMID:  16485046     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Epidemiological information on patients with acute coronary syndromes managed in specialized cardiac centres is limited. OBJECTIVE: To report the evolution of demographics, treatment and outcome of patients admitted to a tertiary coronary care unit (CCU) over a 17-year period. METHODS: A prospective database of 18,719 patients admitted from April 1986 to March 2003 in a 21-bed CCU was analyzed. RESULTS: From 1986 to 2003, the number of admissions increased from 937 to 1577 per year, while the length of stay declined from 7.5 to 3.5 days. The mean age increased from 58.4 to 63.4 years, and the proportion of men remained stable at approximately 70%. The use of coronary angiograms increased from 49.8% to 81.1% in all patients, while fibrinolysis dropped to 0.4%. In-hospital mortality decreased from 9% to 1.5%. The percentage of overall instrumentation (arterial line, central venous catheter, temporary pacemaker, Swan-Ganz catheter and intra-aortic balloon pump) decreased from 38% to 8.1%. From 1995 to 2003, the proportion of stenting during percutaneous transluminal coronary angioplasty increased dramatically from 0% to 86%. In the past five years, surgical revascularization has remained stable at approximately 20% of all admissions. The proportion of patients discharged with a noncoronary chest pain diagnosis has remained constant at approximately 4%. INTERPRETATION: There has been a tremendous increase in efficiency, with an approximate doubling of the admissions turnover rate in a tertiary CCU. Patients with acute coronary syndromes are stratified faster and treated more invasively. Therapeutic advances are reflected by an almost linear 0.5% per year decrease in in-hospital mortality.
Authors:
Jean-Pierre S Awaida; Jocelyn Dupuis; Pierre Théroux; Guy Pelletier; Michel Joyal; Pierre De Guise; Serge Doucet; Luc Bilodeau; Bernard Thibault; Jean-Francois Tanguay; Richard Gallo; Jean Grégoire; Philippe L L'Allier; Laurent Macle; Anil Nigam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  22     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-17     Completed Date:  2006-03-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
Affiliation:
Research Centre, Montreal Heart Institute, and Department of Medicine, University of Montreal, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Age Distribution
Angioplasty, Transluminal, Percutaneous Coronary / statistics & numerical data
Cerebral Revascularization / statistics & numerical data
Coronary Care Units / statistics & numerical data*
Coronary Disease / epidemiology*,  therapy*
Demography
Female
Humans
Intra-Aortic Balloon Pumping / statistics & numerical data
Male
Middle Aged
Outcome Assessment (Health Care)
Prospective Studies
Quebec / epidemiology
Retrospective Studies
Sex Distribution
Stents / statistics & numerical data
Treatment Outcome
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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