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Demographics of Orofacial Clefts in Canada from 2002 to 2008.
MedLine Citation:
PMID:  21905911     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: Orofacial clefts such as cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP) are the most frequent congenital anomalies of the head and neck. The purpose of this study was to determine the current demographics for orofacial clefts in Canada. Methods: A request for data from all Canadian provinces (excluding Quebec due to incompatibilities with provincial coding systems) for the fiscal years 2002/03 to 2007/08 was submitted to the Canadian Institute for Health Information (CIHI). Variables evaluated included gender, cleft type, gestational age, birthweight, income quintile, and institution health region. Results: Over the period studied, the prevalence of orofacial clefts ranged from 11.0 to 15.3 per 10,000 live births (1 in 654 to 1 in 909 live births). The distribution of cleft types for live births with orofacial clefts was 17% CL, 41% CP, and 42% CLP, of which CL and CLP were male dominant (62% and 66% male respectively), and CP was female dominant (56% female). Saskatchewan and Manitoba had significantly higher cleft birthrates (p<0.05) compared to the other provinces. Birth weight and gestational age (but not income quintile) were significantly (p<0.0001) lower for orofacial cleft newborns compared to non-cleft newborns. Conclusions: Canada has one of the highest orofacial cleft birthrates in the world (prevalence of 12.7 per 10,000 live births, approximately 1 in 790 live births). This study presents an updated demographic of orofacial clefts in Canadian newborns and may be useful in predicting the burden of anticipated healthcare. Key Words: Oral clefts, demographics.
Authors:
Sabrina Pavri; Christopher R Forrest
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-9
Journal Detail:
Title:  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association     Volume:  -     ISSN:  1545-1569     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102566     Medline TA:  Cleft Palate Craniofac J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a Case Western Reserve University School of Medicine.
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