| Demographic Inference Reveals African and European Admixture in the North American Drosophila melanogaster Population. | |
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MedLine Citation:
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PMID: 23150605 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Drosophila melanogaster spread from sub-Saharan Africa to the rest of the world colonizing new environments. Here, we modeled the joint demography of African (Zimbabwe), European (The Netherlands) and North American (North Carolina) populations using an Approximate Bayesian Computation (ABC) approach. By testing different models (including scenarios with continuous migration), we found that admixture between Africa and Europe most likely generated the North American population, with an estimated proportion of African ancestry of 15%. We also revisited the demography of the ancestral population (Africa) and found-in contrast to previous work-that a bottleneck fits the history of the population of Zimbabwe better than expansion. Finally, we compared the site frequency spectrum of the ancestral population to analytical predictions under the estimated bottleneck model. |
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Authors:
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Pablo Duchen; Daniel Zivkovic; Stephan Hutter; Wolfgang Stephan; Stefan Laurent |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-12 |
Journal Detail:
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Title: Genetics Volume: - ISSN: 1943-2631 ISO Abbreviation: Genetics Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374636 Medline TA: Genetics Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University of Munich. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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