Document Detail

A Delphi Consensus Approach to Challenging Case Scenarios in Moderate-to-Severe Psoriasis: Part 1.
MedLine Citation:
PMID:  23205324     Owner:  NLM     Status:  PubMed-not-MEDLINE    
INTRODUCTION: Traditional clinical trials in psoriasis exclude a significant proportion of patients with complex disease and comorbidities. A consensus panel of 14 experts in the field of psoriasis was formed to conduct a Delphi method exercise to identify difficult-to-treat psoriasis clinical scenarios and to rank treatment approaches.
METHODS: The exercise consisted of both survey questionnaires and a live meeting to review and discuss current data (as of 2009, when the exercise was conducted) and arrive at a consensus for optimal treatment options. Seventy difficult treatment scenarios were identified, and the top 24 were selected for discussion at the live meeting.
RESULTS: Six of the 24 discussed case scenarios are presented in this article (another five are presented in Part 2): (1) psoriasis with human papilloma virus-induced cervical or anogenital dysplasia; (2) concomitant psoriasis and systemic lupus erythematosus; (3) severe psoriatic nail disease causing functional or emotional impairment; (4) psoriasis therapies that potentially reduce cardiovascular morbidity and mortality; (5) older patients (≥65 years of age) with psoriasis; and (6) severe scalp psoriasis that is unresponsive to topical therapy.
CONCLUSION: The Delphi exercise resulted in guidelines for practicing physicians to utilize when confronted with challenging patients with psoriasis.
Bruce E Strober; Jennifer Clay Cather; David Cohen; Jeffrey J Crowley; Kenneth B Gordon; Alice B Gottlieb; Arthur F Kavanaugh; Neil J Korman; Gerald G Krueger; Craig L Leonardi; Sergio Schwartzman; Jeffrey M Sobell; Gary E Solomon; Melodie Young
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Publication Detail:
Type:  Journal Article     Date:  2012-03-17
Journal Detail:
Title:  Dermatology and therapy     Volume:  2     ISSN:  2193-8210     ISO Abbreviation:  Dermatol Ther (Heidelb)     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-12-09     Completed Date:  2013-12-09     Revised Date:  2013-12-16    
Medline Journal Info:
Nlm Unique ID:  101590450     Medline TA:  Dermatol Ther (Heidelb)     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  1     Citation Subset:  -    
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