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Delivery in female kidney transplant recipients with hepatitis C virus infection: is it safe for mother and newborn?
MedLine Citation:
PMID:  22878070     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The aim of this report is to evaluate whether pregnancy is a risk factor for poor outcome of infection with hepatitis C virus or for allograft deterioration among kidney transplant recipients. The first case was in a 41-year-old pregnant kidney transplant recipient with hypercreatinemia and a history of toxic hepatitis. The second case was treated with interferon before transplant. Tacrolimus-based immunosuppressive regimens were used during the pregnancies. Hypertension complicated both pregnancies, and the pregnancies ended with cesarean delivery at preterm and term with healthy but low-weight newborns. The first patient became positive for hepatitis C virus RNA after pregnancy without a flare in transaminase level. Antibodies to hepatitis C virus were negative in the newborns. In conclusion, pregnancy should be promoted for kidney recipients infected with hepatitis C virus who have stable graft and liver function.
Authors:
Nevin Yilmaz; Ugur Eser Yilmaz; Aysun Unal; Ethem Unal; Izzet Titiz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Progress in transplantation (Aliso Viejo, Calif.)     Volume:  22     ISSN:  1526-9248     ISO Abbreviation:  Prog Transplant     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-08-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100909380     Medline TA:  Prog Transplant     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-4     Citation Subset:  N    
Affiliation:
Mugla University School of Medicine, Mugla, Turkey.
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