Document Detail


Delirium: is sleep important?
MedLine Citation:
PMID:  23040286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Delirium and poor sleep quality are common and often co-exist in hospitalised patients. A link between these disorders has been hypothesised but whether this link is a cause-and-effect relationship or simply an association resulting from shared mechanisms is yet to be determined. Potential shared mechanisms include: abnormalities of neurotransmitters, tissue ischaemia, inflammation and sedative exposure. Sedatives, while decreasing sleep latency, often cause a decrease in slow wave sleep and stage rapid eye movement (REM) sleep and therefore may not provide the same restorative properties as natural sleep. Mechanical ventilation, an important cause of sleep disruption in intensive care unit (ICU) patients, may lead to sleep disruption not only from the discomfort of the endotracheal tube but also as a result of ineffective respiratory efforts and by inducing central apnoea events if not properly adjusted for the patient's physiologic needs. When possible, efforts should be made to optimise the patient-ventilator interaction to minimise sleep disruptions.
Authors:
Paula L Watson; Piero Ceriana; Francesco Fanfulla
Related Documents :
7111916 - 2,3-diphosphoglycerate in high- and low-altitude populations of the deer mouse.
2380176 - Ligand binding to a hemoprotein lacking the distal histidine. the myoglobin from aplysi...
24637426 - A neuron-glia interaction involving gaba transaminase contributes to sleep loss in slee...
21818516 - Central serous chorioretinopathy associated with topical corticosteroids in a patient w...
2235136 - Influence of carotid denervation on the arousal and cardiopulmonary responses to upper ...
15513026 - Handedness and eye-dominance: a meta-analysis of their relationship.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical anaesthesiology     Volume:  26     ISSN:  1878-1608     ISO Abbreviation:  Best Pract Res Clin Anaesthesiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-10-08     Completed Date:  2013-03-01     Revised Date:  2013-10-30    
Medline Journal Info:
Nlm Unique ID:  101121446     Medline TA:  Best Pract Res Clin Anaesthesiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  355-66     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Medicine, Division of Allergy, Pulmonary, Critical Care and Sleep Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. paula.l.watson@vanderbilt.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Delirium / complications,  etiology*,  prevention & control
Hospitalization
Humans
Hypnotics and Sedatives / pharmacology,  therapeutic use
Intensive Care Units
Respiration, Artificial / adverse effects,  methods
Sleep Deprivation / complications,  etiology*,  prevention & control
Sleep Disorders / complications,  etiology*,  prevention & control
Sleep, REM / physiology
Grant Support
ID/Acronym/Agency:
KL2 RR024977/RR/NCRR NIH HHS; KL2 TR000446/TR/NCATS NIH HHS; TL1 RR024978/RR/NCRR NIH HHS; TL1 TR000447/TR/NCATS NIH HHS; UL1 RR024975/RR/NCRR NIH HHS; UL1 TR000445/TR/NCATS NIH HHS
Chemical
Reg. No./Substance:
0/Hypnotics and Sedatives
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Delirium in the fast-track surgery setting.
Next Document:  Delirium detection and monitoring outside the ICU.