Document Detail


Delineation of the nucleus centre median by proton density weighted magnetic resonance imaging at 3 T.
MedLine Citation:
PMID:  20173580     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To demonstrate that proton density weighted magnetic resonance imaging (MRI) at 3 T accomplishes delineation of the centre median (CM) complex from surrounding thalamic tissue and may improve targeting accuracy in stereotactic neurosurgery. METHODS: Five healthy subjects (1 man, 4 women; age range 22-35 years) underwent high-resolution MRI at 3 T with different imaging parameters in order to optimize the direct visualization of the CM. RESULTS: In healthy subjects, the CM complex of the thalamus can be reliably contrasted on axially oriented slices by means of proton density weighted turbo-spin-echo MRI. An in-plane resolution of at least 0.6 x 0.6 mm2 is crucial at a slice thickness between 2 and 3 mm. Effective suppression of head motion is essential. CONCLUSION: MRI-based delineation of the CM could have therapeutic potential to facilitate target determination for neuromodulation in stereotactic neurosurgery.
Authors:
Martin Kanowski; J?rgen Voges; Claus Tempelmann
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurosurgery     Volume:  66     ISSN:  1524-4040     ISO Abbreviation:  Neurosurgery     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-06-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E121-3; discussion E123     Citation Subset:  IM    
Affiliation:
Department of Neurology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. martin.kanowski@medizin.uni-magdeburg.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Mapping / methods*
Female
Humans
Intralaminar Thalamic Nuclei / anatomy & histology*,  surgery
Magnetic Resonance Imaging / methods*
Male
Neuronavigation / methods
Preoperative Care / methods
Stereotaxic Techniques
Thalamus / anatomy & histology*,  surgery
Young Adult

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