| Delimitation of the time of death by immunohistochemical detection of thyroglobulin. | |
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MedLine Citation:
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PMID: 10842031 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To improve the possibilities to delimit the time of death after longer laytime it was examined if this is possible by immunohistochemical detection of thyroglobulin. The results show that in our examination material the colloid and the follicular cells of the thyroid glands of up to 5-day-old corpses produce a positive immunoreaction towards thyroglobulin in all cases whereas none of the corpses older than 13 days show such a reaction. This means that in case of a negative immunoreaction the time of death can be assumed to lie more than 6 days before the autopsy. The fact that a negative immunoreaction occurs consistently after 13 days leads to the conclusion that when thyroglobulin has been stained in a specimen, the death of the respective person must lie a maximum of 12 days earlier, whereby these time-limits may change in considerably different surrounding conditions. |
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Authors:
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F Wehner; H D Wehner; M C Schieffer; J Subke |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Forensic science international Volume: 110 ISSN: 0379-0738 ISO Abbreviation: Forensic Sci. Int. Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-08-01 Completed Date: 2000-08-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7902034 Medline TA: Forensic Sci Int Country: IRELAND |
Other Details:
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Languages: eng Pagination: 199-206 Citation Subset: IM |
Affiliation:
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Institut für Gerichtliche Medizin der Universität Tübingen, Nägelestrasse 5, D-72074, Tübingen, Germany. frank.wehner@uni-tuebingen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Death* Humans Immunohistochemistry Postmortem Changes Thyroglobulin / analysis* Thyroid Gland / chemistry* Time Factors |
| Chemical | |
Reg. No./Substance:
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9010-34-8/Thyroglobulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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