| Deletion analysis of DMD/BMD children in Singapore using multiplex polymerase chain reaction (PCR) technique. | |
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MedLine Citation:
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PMID: 1433447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-three children suffering from Duchenne/Becker muscular dystrophy (DMD/BMD) in Singapore were analysed using the multiplex polymerase chain reaction (PCR) technique. Deletions were found in 14 cases. One rare case of total deletion of all nine exons was observed. This is the first DMD/BMD deletion analysis on South East Asian children. This technique for screening deletions was informative in 61 per cent of the local cases and would be useful for rapid diagnosis of deletion cases of DMD/BMD. |
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Authors:
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P S Lai; J S Tay; P S Low; W L Lee; G A Koh; G C Gan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of tropical pediatrics Volume: 38 ISSN: 0142-6338 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 1992 Oct |
Date Detail:
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Created Date: 1992-12-23 Completed Date: 1992-12-23 Revised Date: 2006-03-28 |
Medline Journal Info:
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Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 224-7 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, National University of Singapore. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Child, Preschool Chromosome Deletion Humans Male Muscular Dystrophies / diagnosis*, genetics Polymerase Chain Reaction* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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