Document Detail


Deletion analysis of DMD/BMD children in Singapore using multiplex polymerase chain reaction (PCR) technique.
MedLine Citation:
PMID:  1433447     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-three children suffering from Duchenne/Becker muscular dystrophy (DMD/BMD) in Singapore were analysed using the multiplex polymerase chain reaction (PCR) technique. Deletions were found in 14 cases. One rare case of total deletion of all nine exons was observed. This is the first DMD/BMD deletion analysis on South East Asian children. This technique for screening deletions was informative in 61 per cent of the local cases and would be useful for rapid diagnosis of deletion cases of DMD/BMD.
Authors:
P S Lai; J S Tay; P S Low; W L Lee; G A Koh; G C Gan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  38     ISSN:  0142-6338     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1992-12-23     Completed Date:  1992-12-23     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  224-7     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, National University of Singapore.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Chromosome Deletion
Humans
Male
Muscular Dystrophies / diagnosis*,  genetics
Polymerase Chain Reaction*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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