| Deletion 7q22 in uterine leiomyoma. A cytogenetic review. | |
| | |
MedLine Citation:
|
PMID: 8275445 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The cytogenetic patterns of uterine leiomyomas have been extensively investigated, and cases characterized by specific clonal changes have been documented in detail. In these tumors one of the cytogenetic changes frequently observed has been a del(7), particularly del(7)(q22), usually as a sole anomaly. This is confirmed by our experience and by reports in the literature. The fact that del(7) is one of the most common abnormalities in leiomyoma raises the question of its role in tumor development. The main purpose of this review is to analyze the above aspect and to interpret its possible meaning. Our findings on cytogenetic abnormalities of chromosome 7 in leiomyoma, together with those reported in the literature, are reviewed and discussed. A listing of the genes located at 7q22 is also presented. |
| | |
Authors:
|
Y Y Ozisik; A M Meloni; U Surti; A A Sandberg |
Related Documents
:
|
17694975 - Extensive iliac vein thrombosis as a rare complication of a uterine leiomyoma: a case r... 12605285 - Leiomyosarcoma of the popliteal vein. 1884945 - The value of ri scintigraphy and angiography in small intestinal bleeding--report of ei... 20704475 - An infantile leiomyosarcoma that metastasized from the small intestine to the adrenal g... 6757695 - Primary hepatic lymphoma: two case reports and a review of the literature. 6846305 - Bilateral pancreatic pleural effusions: a case report and literature review. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
|
Title: Cancer genetics and cytogenetics Volume: 71 ISSN: 0165-4608 ISO Abbreviation: Cancer Genet. Cytogenet. Publication Date: 1993 Nov |
Date Detail:
|
Created Date: 1994-02-04 Completed Date: 1994-02-04 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 7909240 Medline TA: Cancer Genet Cytogenet Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1-6 Citation Subset: IM |
Affiliation:
|
Cancer Center of Southwest Biomedical Research Institute, Scottsdale, Arizona 85251. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Chromosome Deletion* Chromosomes, Human, Pair 7* Female Humans Leiomyoma / genetics* Uterine Neoplasms / genetics* |
| Grant Support | |
ID/Acronym/Agency:
|
CA 41183/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chemohormone therapy of metastatic melanoma with megestrol acetate plus dacarbazine, carmustine, and...
Next Document: Cloning and characterization of the human t(3;6)(p14;p11) translocation breakpoint associated with h...