Document Detail

Deletion of 3p25-->pter in a primary follicular thyroid carcinoma and its metastasis.
MedLine Citation:
PMID:  7509630     Owner:  NLM     Status:  MEDLINE    
We report the cytogenetic analysis of a follicular thyroid carcinoma and its bone metastasis. Both lesions had identical chromosomal abnormalities, with a der(3)t(2;3)(q13;p25) as the most likely primary clonal alteration. Our findings corroborate previous observations of frequent 3p deletions in thyroid follicular carcinomas and suggest that the minimal chromosomal region of loss in these tumors is 3p25-->pter.
L Roque; S Castedo; A Clode; J Soares
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Genes, chromosomes & cancer     Volume:  8     ISSN:  1045-2257     ISO Abbreviation:  Genes Chromosomes Cancer     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1994-04-07     Completed Date:  1994-04-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9007329     Medline TA:  Genes Chromosomes Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  IM    
Institute for Molecular Pathology and Immunology, University of Porto-IPATIMUP, Portugal.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenocarcinoma, Follicular / genetics*,  secondary
Chromosome Aberrations
Chromosome Banding
Chromosome Deletion*
Chromosomes, Human, Pair 3*
Thyroid Neoplasms / genetics*,  secondary
Tumor Cells, Cultured

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Whole chromosome 17 loss in ovarian cancer.
Next Document:  NMR-derived solution conformations of a hybrid synthetic peptide containing multiple epitopes of env...