Document Detail


Deletion of 3p25-->pter in a primary follicular thyroid carcinoma and its metastasis.
MedLine Citation:
PMID:  7509630     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the cytogenetic analysis of a follicular thyroid carcinoma and its bone metastasis. Both lesions had identical chromosomal abnormalities, with a der(3)t(2;3)(q13;p25) as the most likely primary clonal alteration. Our findings corroborate previous observations of frequent 3p deletions in thyroid follicular carcinomas and suggest that the minimal chromosomal region of loss in these tumors is 3p25-->pter.
Authors:
L Roque; S Castedo; A Clode; J Soares
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Genes, chromosomes & cancer     Volume:  8     ISSN:  1045-2257     ISO Abbreviation:  Genes Chromosomes Cancer     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1994-04-07     Completed Date:  1994-04-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9007329     Medline TA:  Genes Chromosomes Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  IM    
Affiliation:
Institute for Molecular Pathology and Immunology, University of Porto-IPATIMUP, Portugal.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma, Follicular / genetics*,  secondary
Aged
Chromosome Aberrations
Chromosome Banding
Chromosome Deletion*
Chromosomes, Human, Pair 3*
Female
Humans
Karyotyping
Thyroid Neoplasms / genetics*,  secondary
Tumor Cells, Cultured

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