Document Detail

Delays in thrombolytic therapy in acute myocardial infarction: an audit from the east coast of peninsular Malaysia.
MedLine Citation:
PMID:  9285018     Owner:  NLM     Status:  MEDLINE    
The objectives of this study were to evaluate the time delays between the onset of symptoms and admission to hospital and provision of thrombolytic therapy in patients with suspected acute myocardial infarction; and to examine the accuracy of the clinical diagnosis and the therapeutic decision on thrombolysis in these patients. An observational study of 96 patients with suspected myocardial infarction was undertaken over a period of 15 months in the Coronary Care Unit of Hospital Kuala Terengganu. Seventy per cent of the patients arrived in the hospital within 6 hours of the onset of symptoms. After arrival in the emergency room, it took a median time of 85 minutes before the administration of thrombolytic therapy. Of the 67 patients who were given thrombolysis, 46 were treated within 6 hours of the onset of symptoms. About a quarter of patients said that they had delayed seeking treatment at the hospital. Treatment delays occurring in the hospital were mainly due to admission procedures as well as late diagnosis. Eighty-one patients had confirmed myocardial infarction of whom 59 received thrombolytic therapy. Eight patients receiving thrombolytic therapy had no confirmation of myocardial infarctions. Improvements in diagnostic accuracy and reduction of delays in the provision of thrombolytic therapy could be achieved by better training of health care staff as well as by further streamlining of admission procedures.
Y K Loke; S L Hwang; M H Tan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  26     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-11-04     Completed Date:  1997-11-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  285-9     Citation Subset:  IM    
Department of Medicine, Hospital Kuala Terengganu, Malaysia.
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MeSH Terms
Clinical Protocols
Coronary Care Units
Medical Audit
Myocardial Infarction / diagnosis,  drug therapy*
Thrombolytic Therapy*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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