Document Detail

Delayed visual maturation: ophthalmic and neurodevelopmental aspects.
MedLine Citation:
PMID:  1701741     Owner:  NLM     Status:  MEDLINE    
Delayed visual maturation (DVM) can present as an isolated anomaly (type 1A), but can be compounded by perinatal problems (type 1B), severe neurodevelopmental delay (type 2), or ocular anomalies/nystagmus (type 3), in which group the common feature appears to be nystagmus. The neurodevelopmental and ophthalmic aspects of 26 infants with DVM were studied. Onset of visual improvement, rate of acquisition of normal vision and eventual outcome were studied quantitatively, using an adaptation of the acuity card procedure. Neurodevelopmental assessment was performed after visual improvement. The results support the long-held clinical impression that if blindness is the presenting feature, neurodevelopmental outlook is excellent. DVM could represent a defect in the extrageniculostriate visual system, and the onset of vision in all types--and the development of nystagmus in type 3--could herald the emergence of geniculostriate function.
J Tresidder; A R Fielder; J Nicholson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  32     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-01-28     Completed Date:  1991-01-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  872-81     Citation Subset:  IM    
University of Leicester.
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MeSH Terms
Blindness / congenital
Child, Preschool
Cohort Studies
Developmental Disabilities / diagnosis*
Diagnosis, Differential
Eye Diseases / congenital*,  diagnosis
Follow-Up Studies
Infant, Newborn
Infant, Premature, Diseases / diagnosis*
Nervous System Diseases / congenital*,  diagnosis
Nystagmus, Pathologic / congenital
Strabismus / congenital
Vision Disorders / congenital*,  diagnosis
Vision Tests
Visual Acuity
Comment In:
Dev Med Child Neurol. 1991 Feb;33(2):181   [PMID:  2015989 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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