Document Detail

Delayed tricuspid valve ascent and descent components in pulmonary hypertension.
MedLine Citation:
PMID:  17980445     Owner:  NLM     Status:  MEDLINE    
Even though pulmonary hypertension (PH) results in right ventricular (RV) dilatation and contractile dysfunction; the exact mechanism(s) remain to be identified. RV fractional area change (RVFAC), right atrial (RA) areas, tricuspid annular plane systolic excursion (TAPSE), and systolic (sEI) eccentricity index were measured in 19 PH patients and 11 individuals without PH. Furthermore, time to maximal peak (tmp) TV annular ascent and descent intervals were obtained and corrected for heart rate. Finally, P wave and QRS interval durations as well as heart rates were also measured. As expected, PH results in lower RVFAC and TAPSE, smaller sEI and larger RA areas. More interestingly, longer P wave and QRS durations without significant difference in heart rate are noted in PH patients. Similarly, it took longer to reach maximal TV annular ascent as well as annular descent in PH patients than in those patients without PH. PH significantly prolongs both electrical as well as mechanical events related to annular motion, implying that PH contributes to increased atrial as well ventricular activation times. The nature of this functional coupling between RA and RV necessitates further study.
Angel López-Candales; Beth Gulyasy; Kathy Edelman; Raveen Bazaz
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Publication Detail:
Type:  Letter; Research Support, Non-U.S. Gov't     Date:  2007-11-05
Journal Detail:
Title:  International journal of cardiology     Volume:  131     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-12     Completed Date:  2009-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  399-402     Citation Subset:  IM    
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MeSH Terms
Hypertension, Pulmonary / complications,  physiopathology*,  ultrasonography
Time Factors
Tricuspid Valve / physiopathology*,  ultrasonography
Ventricular Dysfunction, Right / etiology

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