Document Detail

Delayed treatment with GnRH agonist, hCG and progesterone and reduced embryonic mortality in buffaloes.
MedLine Citation:
PMID:  18706685     Owner:  NLM     Status:  MEDLINE    
The present study examined the effect of delayed treatment with tropic hormones and progesterone (P4) on embryonic mortality in buffaloes. Buffaloes with a conceptus on Day 25 after AI were assigned to the following treatments: Control (n=41), i.m. physiological saline; GnRH agonist (n=36), i.m. 12 microg buserelin acetate; hCG (n=33), i.m. 1500 IU hCG; P4 (n=38), i.m. 341 mg P4 every 4 days on three occasions. Control buffaloes had an embryonic mortality of 41.4% (17/41) between Days 25 and 45, and this was reduced (P<0.01) by treatment with GnRH agonist (11.1%, 4/36), hCG (9.0%, 3/33) and P4 (13.1%, 5/38). On Day 45, buffaloes treated with hCG and which ovulated had greater (P<0.05) concentrations of P(4) in whey (453 +/- 41 pg/ml) than buffaloes in the same treatment that did not ovulate (297 +/- 32 pg/ml). A similar but non-significant trend was observed for buffaloes treated with GnRH agonist. It was concluded from the findings that the treatment of buffaloes on Day 25 after AI with tropic hormones or P4 is beneficial to processes associated with embryonic implantation.
G Campanile; D Vecchio; R Di Palo; G Neglia; B Gasparrini; A Prandi; L Zicarelli; M J D'Occhio
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-08-15
Journal Detail:
Title:  Theriogenology     Volume:  70     ISSN:  0093-691X     ISO Abbreviation:  Theriogenology     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-14     Completed Date:  2009-03-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421510     Medline TA:  Theriogenology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1544-9     Citation Subset:  IM    
DISCIZIA, Faculty of Veterinary Medicine, Federico II University, V.F. Delpino 1, Naples 80137, Italy.
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MeSH Terms
Abortion, Veterinary / prevention & control
Buffaloes / physiology*
Buserelin / administration & dosage,  pharmacology*
Chorionic Gonadotropin / administration & dosage,  pharmacology*
Fertility Agents, Female / administration & dosage,  pharmacology
Gonadotropin-Releasing Hormone / agonists*
Progesterone / administration & dosage,  pharmacology*
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Fertility Agents, Female; 33515-09-2/Gonadotropin-Releasing Hormone; 57-83-0/Progesterone; 57982-77-1/Buserelin

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