Document Detail


Delayed ovulation and monozygotic twinning.
MedLine Citation:
PMID:  1031545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aiming to show that delayed ovulation may induce MZ twinning, follicular maturation was induced in the rabbit by a small quantity of Pregnant Mare Serum Gonadotropin (16 UI four times): coitus, which induces ovulation in the rabbit, was delayed 60 hours after the last injection. From the 387 blastocysts obtained after this treatment, 6 (1.5%) were pairs of MZ twins, twinning being otherwise exceptional in the rabbit. Other anomalies were shown by the embryos, apparently related to a deficient quality of the eggs: high embryonic mortality (62% vs. 27% in controls) and chromosomal anomalies (20%) such as trisomies, triploidies, and chimaeras. The relation between MZ twinning, chromosomal anomalies, and embryonic mortality induced by delayed ovulation, could be connected and related to the poor perinatal conditions frequently observed in human MZ twins.
Authors:
O Bomsel-Helmreich; E Papiernik-Berkhauer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta geneticae medicae et gemellologiae     Volume:  25     ISSN:  0001-5660     ISO Abbreviation:  Acta Genet Med Gemellol (Roma)     Publication Date:  1976  
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370314     Medline TA:  Acta Genet Med Gemellol (Roma)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  73-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Survival
Chromosome Aberrations / embryology
Chromosome Disorders
Death
Disease Models, Animal
Diseases in Twins
Female
Humans
Infant, Newborn
Maternal Age
Menstruation
Ovulation*
Ovum / physiology
Pregnancy
Rabbits
Twins*
Twins, Monozygotic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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