Document Detail

Delayed ovulation and monozygotic twinning.
MedLine Citation:
PMID:  1031545     Owner:  NLM     Status:  MEDLINE    
Aiming to show that delayed ovulation may induce MZ twinning, follicular maturation was induced in the rabbit by a small quantity of Pregnant Mare Serum Gonadotropin (16 UI four times): coitus, which induces ovulation in the rabbit, was delayed 60 hours after the last injection. From the 387 blastocysts obtained after this treatment, 6 (1.5%) were pairs of MZ twins, twinning being otherwise exceptional in the rabbit. Other anomalies were shown by the embryos, apparently related to a deficient quality of the eggs: high embryonic mortality (62% vs. 27% in controls) and chromosomal anomalies (20%) such as trisomies, triploidies, and chimaeras. The relation between MZ twinning, chromosomal anomalies, and embryonic mortality induced by delayed ovulation, could be connected and related to the poor perinatal conditions frequently observed in human MZ twins.
O Bomsel-Helmreich; E Papiernik-Berkhauer
Related Documents :
6198435 - Preimplantation development of the primate embryo after in vitro fertilization.
19022875 - Thioglycolic acid inhibits mouse oocyte maturation and affects chromosomal arrangement ...
20479065 - Snp microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stag...
6683925 - Follicular growth and intraovarian and extraovarian oocyte release after daily injectio...
10716925 - Hsp90 is a core centrosomal component and is required at different stages of the centro...
6132455 - Misregulation versus mutation in the alteration of gene expression by carcinogens throu...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta geneticae medicae et gemellologiae     Volume:  25     ISSN:  0001-5660     ISO Abbreviation:  Acta Genet Med Gemellol (Roma)     Publication Date:  1976  
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370314     Medline TA:  Acta Genet Med Gemellol (Roma)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  73-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cell Survival
Chromosome Aberrations / embryology
Chromosome Disorders
Disease Models, Animal
Diseases in Twins
Infant, Newborn
Maternal Age
Ovum / physiology
Twins, Monozygotic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Monoamniotic twins.
Next Document:  Triplet pregnancy in a subfertile woman treated with clomiphene citrate.