Document Detail

Delayed-onset slipped capital femoral epiphysis: case report of association with pituitary tumor.
MedLine Citation:
PMID:  20463986     Owner:  NLM     Status:  MEDLINE    
Slipped capital femoral epiphysis (SCFE) is an affliction of the hip presenting in adolescent children. There are several theories regarding the pathological cause of SCFE. The hormonal milieu during adolescence, combined with a deficiency in the physeal area of the growth plate, has been postulated as a possible etiology for its specific onset. In atypical circumstances, the early or late onset of SCFE may occur in the setting of unusual hormonal influences. This hormonal imbalance may be secondary to an underlying endocrinopathy-for example, hypothyroidism or hypogonadism. In this case, our patient presented with a clinically and radiographically unstable slip at the age of 22 years. His physical characteristics, along with confirmatory laboratory values and radiographs, indicated that the patient suffered from a disorder of delayed secondary growth. Subsequent thorough work-up revealed a large benign pituitary tumor that was causing severe panhypopituitarism. This article describes the presentation, diagnostic work-up and treatment of our patient with a delayed-onset SCFE in the setting of a pituitary tumor.
Robert L Brady; Andrew Price
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of orthopedics (Belle Mead, N.J.)     Volume:  39     ISSN:  1934-3418     ISO Abbreviation:  Am J. Orthop.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502918     Medline TA:  Am J Orthop (Belle Mead NJ)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  137-40     Citation Subset:  IM    
Department of Orthopaedic Surgery, Norwalk Hospital, Connecticut, USA.
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MeSH Terms
Craniopharyngioma / complications*,  surgery
Epiphyses, Slipped / complications*,  surgery
Femur / surgery
Hypopituitarism / complications,  surgery
Pituitary Neoplasms / complications*,  surgery
Severity of Illness Index
Treatment Outcome
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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