Document Detail

Delayed onset of malignant hyperthermia in desflurane anesthesia.
MedLine Citation:
PMID:  12505945     Owner:  NLM     Status:  MEDLINE    
Animal-experimental studies demonstrate desflurane's trigger effect for malignant hyperthermia (MH). In contrast to other anesthetics, the time interval from exposure to the occurrence of symptoms is much longer with desflurane. This case report focuses on MH induced by desflurane alone.
Christian W Hoenemann; Tobias B Halene-Holtgraeve; Michael Booke; Frank Hinder; Fritz Daudel; Alexander Reich; Hugo Van Aken
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Publication Detail:
Type:  Case Reports; In Vitro; Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  96     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2002-12-30     Completed Date:  2003-01-21     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  165-7, table of contents     Citation Subset:  AIM; IM    
Department of Anesthesiology and Critical CareUniversitätsklinikum Münster, Germany.
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MeSH Terms
Anesthesia, Inhalation / adverse effects*
Anesthetics, Inhalation / adverse effects*
Dantrolene / therapeutic use
Hemodynamics / drug effects
Isoflurane / adverse effects*,  analogs & derivatives*
Malignant Hyperthermia / blood,  drug therapy,  physiopathology*
Monitoring, Intraoperative
Muscle Relaxants, Central / therapeutic use
Muscle, Skeletal / drug effects
Orthopedic Procedures
Postoperative Period
Scoliosis / surgery
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Muscle Relaxants, Central; 26675-46-7/Isoflurane; 57041-67-5/desflurane; 7261-97-4/Dantrolene
Comment In:
Anesth Analg. 2003 Jul;97(1):295; author reply 295   [PMID:  12818992 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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