Document Detail

Delayed-onset dystonia following recovery from central pontine myelinolysis.
MedLine Citation:
PMID:  1362667     Owner:  NLM     Status:  MEDLINE    
We report on a 47-year-old female patient with Sheehan's syndrome who developed delayed-onset dystonia following recovery from central pontine myelinolysis. The dystonia was observed in the head, neck and limbs during active movement. MRI scan demonstrated a discrete lesion in the central pons without involving the basal ganglia. The action dystonia was markedly improved by giving trihexyphenidyl. The patient showed that generalized dystonia can be induced by an isolated pontine myelinolysis. There have been four other cases reported in the literature. On reviewing all five cases, we conclude that delayed-onset dystonia following central pontine myelinolysis usually presents with generalized action dystonia and has a beneficial response to trihexyphenidyl.
C L Wu; C S Lu
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of the Formosan Medical Association = Taiwan yi zhi     Volume:  91     ISSN:  0929-6646     ISO Abbreviation:  J. Formos. Med. Assoc.     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-02-26     Completed Date:  1993-02-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9214933     Medline TA:  J Formos Med Assoc     Country:  HONG KONG    
Other Details:
Languages:  eng     Pagination:  1013-6     Citation Subset:  IM    
Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan R.O.C.
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MeSH Terms
Demyelinating Diseases / complications*
Dystonia / etiology*
Magnetic Resonance Imaging
Middle Aged
Pons / pathology*
Time Factors

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