Document Detail

Delayed onset chloroquine retinopathy: case report.
MedLine Citation:
PMID:  677653     Owner:  NLM     Status:  MEDLINE    
A patient presented with decreased visual acuity and retinal findings compatible with chloroquine retinopathy 5 years after discontinuing regular usage of chloroquine for rheumatoid arthritis. A review of the literature on chloroquine retinopathy is outlined. In addition, the characteristic findings including fluorescein angiography, retinal physiologic studies, and symptoms are reviewed. Chloroquine retinopathy is dose related and essentially irreversible and often progressive once typical findings are noted. To our knowledge very delayed onset of chloroquine retinopathy is a relatively rare phenomenon but the medical and ophthalmic communities must be alerted to the possibly severe complications of this iatrogenic disease entity.
L J Martin; R L Bergen; H R Dobrow
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of ophthalmology     Volume:  10     ISSN:  0003-4886     ISO Abbreviation:  Ann Ophthalmol     Publication Date:  1978 Jun 
Date Detail:
Created Date:  1978-09-25     Completed Date:  1978-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210137     Medline TA:  Ann Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  723-6     Citation Subset:  IM    
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MeSH Terms
Chloroquine / adverse effects*
Dose-Response Relationship, Drug
Macula Lutea / pathology
Middle Aged
Retina / pathology
Retinal Diseases / chemically induced*,  pathology
Time Factors
Vision Disorders / chemically induced*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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