Document Detail

Delayed neurotoxicity induced by organophosphorus compounds in the wild mallard duckling: effect of leptophos.
MedLine Citation:
PMID:  82597     Owner:  NLM     Status:  MEDLINE    
Feeding of 260 ppm of leptophos to mallard ducklings caused delayed neurotoxicity similar to that reported for hens. Thus leptophos caused ataxia, with subsequent paralysis, loss of appetite, and slow-down in the growth rate of the treated birds. Spinal lesions were identical in morphology and distribution to those seen in hens following leptophos administration. The severity of histologic changes correlated both with the clinical condition and the duration of intoxication.
R A Herin; A A Komeil; D G Graham; A Curley; M B Abou-Donia
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of environmental pathology and toxicology     Volume:  1     ISSN:  0146-4779     ISO Abbreviation:  J Environ Pathol Toxicol     Publication Date:    1978 Jan-Feb
Date Detail:
Created Date:  1979-02-12     Completed Date:  1979-02-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7801245     Medline TA:  J Environ Pathol Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  233-40     Citation Subset:  IM    
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MeSH Terms
Body Weight / drug effects
Ducks / physiology*
Insecticides / toxicity*
Leptophos / toxicity*
Nervous System Diseases / chemically induced*,  pathology
Sciatic Nerve / pathology
Spinal Cord / pathology
Time Factors
Reg. No./Substance:
0/Insecticides; 21609-90-5/Leptophos

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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