Document Detail


Delayed maturation of the interstitial cells of Cajal: a new diagnosis for transient neonatal pseudoobstruction. Report of two cases.
MedLine Citation:
PMID:  9473109     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case histories of two neonates presenting with intestinal pseudoobstruction are presented. One boy infant was premature and the girl infant was full term. Both patients needed a defunctioning ileostomy, and biopsy findings of the intestine in both patients showed a lack of interstitial cells of Cajal (ICC). At the time of closure of the ileostomies to restore intestinal continuity, repeat biopsy results showed a normal pattern of distribution of ICC. Delay in the development of ICC in the gastrointestinal tract may be a cause of intestinal pseudoobstruction in the newborn.
Authors:
S E Kenny; J M Vanderwinden; R J Rintala; M G Connell; D A Lloyd; J J Vanderhaegen; M H De Laet
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  33     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-03-20     Completed Date:  1998-03-20     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  94-8     Citation Subset:  IM    
Affiliation:
Department of Pediatric Surgery, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Colon / pathology*
Female
Gastrointestinal Motility / physiology
Humans
Ileostomy
Ileum / pathology*
Infant, Newborn
Intestinal Pseudo-Obstruction / diagnosis,  etiology*,  therapy
Male
Muscle, Smooth / pathology*
Parenteral Nutrition, Total
Proto-Oncogene Proteins c-kit / metabolism
Stem Cell Factor / metabolism
Chemical
Reg. No./Substance:
0/Stem Cell Factor; EC 2.7.10.1/Proto-Oncogene Proteins c-kit

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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