| Delayed hypersensitivity to thimerosal in soft contact lens wearers. | |
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MedLine Citation:
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PMID: 7322498 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-eight patients were examined because of ocular redness, irritation, and corneal changes apparently related to soft contact lens wear. The corneal changes were transient and ranged from faint epithelial opacities to a coarse, punctate epithelial keratopathy. Solutions containing thimerosal had been used by all of the patients for lens care, and 31 responded to an ocular challenge with a thimerosal-preserved lens lubricant. Twenty-seven of these 31 also reacted to thimerosal patch testing. The 31 resumed lens wear with relief of symptoms by using unit-dose, preservative-free saline for lens storage and thermal disinfection. A hypersensitivity to thimerosal was assumed responsible for the clinical findings. |
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Authors:
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L A Wilson; J McNatt; R Reitschel |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Ophthalmology Volume: 88 ISSN: 0161-6420 ISO Abbreviation: Ophthalmology Publication Date: 1981 Aug |
Date Detail:
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Created Date: 1982-03-13 Completed Date: 1982-03-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 804-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Contact Lenses, Hydrophilic* Drug Hypersensitivity / etiology* Ethylmercury Compounds / adverse effects* Female Humans Hypersensitivity, Delayed* Keratoconjunctivitis / chemically induced* Male Middle Aged Ophthalmic Solutions Patch Tests Preservatives, Pharmaceutical / adverse effects Thimerosal / administration & dosage, adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Ethylmercury Compounds; 0/Ophthalmic Solutions; 0/Preservatives, Pharmaceutical; 54-64-8/Thimerosal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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