| Delayed gastric emptying in patients with Prader Willi Syndrome. | |
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MedLine Citation:
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PMID: 21175084 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A 15 year old girl with Prader-Willi Syndrome (PWS) died of gastric rupture. Systematic literature research revealed seven case reports of PWS patients with acute gastric dilatation, two had a lethal course. The objective of this study was to determine if delayed gastric emptying in PWS patients might contribute to gastric dilatation. METHODS: Gastric emptying was measured in eight patients with PWS by nucleotid scintigraphy after a standardized test meal. RESULTS: Median age was 17.8 years (range 10.1-19.5). Median BMI of the male patients was 29.5 (range 18.4-34.8), of the female patients 28 (range 20.0-44.8). Half time of gastric emptying was delayed in five of the eight patients (median 78.5 minutes, range 59-134). CONCLUSION: Scintigraphic measurement of gastric emptying in eight PWS patients revealed delay in comparison to normal values. This might be a risk factor for gastric dilatation and rupture in patients with PWS. |
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Authors:
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T Arenz; A Schwarzer; Th Pfluger; S Koletzko; H Schmidt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 23 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-12-22 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: England |
Other Details:
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Languages: eng Pagination: 867-71 Citation Subset: IM |
Affiliation:
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Inselspital, Children's Hospital of the University Berne. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Female Gastric Dilatation / etiology Gastric Emptying* Humans Male Pain Perception Prader-Willi Syndrome / complications, physiopathology* Young Adult |
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