Document Detail

Delayed diagnosis of primary hyperparathyroidism in a patient with osteoclastoma.
MedLine Citation:
PMID:  22147439     Owner:  NLM     Status:  MEDLINE    
Primary hyperparathyroidism (HPTo) nowadays is most often recognized incidentally in the asymptomatic period as a result of biochemical screening or evaluation of low bone mass. Classical manifestations of the disease are present in about 15-20% of patients. We present the case of a 28-year-old male patient who had been treated for two years for osteoclastoma of the proximal tibia, first by intralesional curettage with cement filling followed by bone grafting, and finally with a reconstructive arthroplasty of the knee joint. The patient had been consulted in different medical centers by at least 14 doctors representing 9 different specialties, but the correct diagnosis of HPTo had not been made, although classic manifestations of the disease had been present for 5-6 years. This suggests that a diagnosis of HPTo is difficult nowadays. Therefore, determination of serum calcium concentration and other markers of calcium and phosphate metabolism should be obligatory in patients with bone lesions.
Daria Baszko-Błaszyk; Maciej Biczysko; Paweł Gut; Ryszard Waśko; Jerzy Sowiński
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ortopedia, traumatologia, rehabilitacja     Volume:  13     ISSN:  2084-4336     ISO Abbreviation:  Ortop Traumatol Rehabil     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-12-07     Completed Date:  2012-05-23     Revised Date:  2012-10-18    
Medline Journal Info:
Nlm Unique ID:  101240146     Medline TA:  Ortop Traumatol Rehabil     Country:  Poland    
Other Details:
Languages:  eng; pol     Pagination:  505-10     Citation Subset:  IM    
Department of Endocrinology, Metabolism and Internal Medicine, Karol Marcinkowski University of Medical Sciences, Poznań, Poland.
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MeSH Terms
Biological Markers / blood
Bone Neoplasms / complications,  diagnosis*,  therapy
Bone Resorption / diagnosis,  etiology*
Calcium / blood
Delayed Diagnosis*
Diagnosis, Differential
Giant Cell Tumor of Bone / diagnosis*,  therapy
Hyperparathyroidism, Primary / blood,  complications*,  diagnosis*
Reg. No./Substance:
0/Biological Markers; 7440-70-2/Calcium

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