| Delayed development of a rhabdomyosarcoma following radiation for a spinal cord glioma. | |
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MedLine Citation:
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PMID: 23296545 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Radiation-induced sarcomas represent a rare delayed-late secondary complication of radiation therapy. Radiation-associated sarcomas are associated with a worse overall prognosis compared to sporadic sarcomas irrespective of histological type. Herein we report a case of a 65-year old man who underwent surgery and radiation therapy for a T4 spinal cord low-grade two astrocytoma in 1965 and presented over 40 years later with spinal cord complex intramedullary tumor involving the thoracic cord with drop metastases in the lumbar spine. Histology from a partial resection of the thoracic spinal tumor revealed a high-grade rhabdomyosarcoma. In addition to the rarity of radiation-induced sarcoma arising following the treatment of a spinal cord glioma, this case study represents one of the first reports of a spinal cord rhabdomyosarcoma arising in this setting. |
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Authors:
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Edmond Mazbani; Robin L Jones; James Fink; Marc C Chamberlain |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-8 |
Journal Detail:
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Title: Journal of neuro-oncology Volume: - ISSN: 1573-7373 ISO Abbreviation: J. Neurooncol. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309335 Medline TA: J Neurooncol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Medicine, University of Washington, Seattle, WA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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